Colorado MS patient returning to Panama for more stem cell therapy

By Travis Khachatoorian
Created: Mon, 05 May 2014 10:21:00 MST
Updated: Mon, 05 May 2014 11:27:10 MST

CLIFTON, Colo. – Even with all the advances in medical sciences over the years, multiple sclerosis remains mysterious in both causes and symptoms. There is no known cure for the disease, but one Clifton resident isn’t waiting on the US government anymore and is planning to fly to Panama for a stem cell therapy.

Pam Claypoole was diagnosed with MS almost a decade ago and has slowly lost the feeling in her legs and right arm. She said since the FDA currently doesn’t approve any stem cell therapies for her disease, she’s planning a second trip to Panama in hopes to improve her condition.

Claypoole said she’s made one trip to the Stem Cell Institute in Panama more than a year ago and was amazed by the effects.

“I felt it made a big difference for me right away,” said Claypoole. “My walking was better, the feeling in my feet was better, I had more energy.”

She emphasized her treatment doesn’t involve unborn fetus stem cells but rather the stem cells taken from healthy birthed babies umbilical cords.

Her family is currently planning a live auction on May 14th at the Western Slope Cattleman’s Livestock Auction in Loma. The event starts at 6 pm, and they’re hoping to collect $20,000 dollars to fund Pam’s therapy in Central America.

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Stem cell therapy for traumatic brain injury – Oswaldo Tapanes

Oswaldo Tapanes received multiple injections of human umbilical cord-derived mesenchymal stem cells and his own bone marrow-derived stem cells over the course of a month both intrathecally (into the spinal fluid) and intravenously at the Stem Cell Institute in Panama. Here is what Mr. Tapanes had to day about his progress thus far:

My name is Oswaldo Tapanes. I have a traumatic brain injury; diagnosed in June 2005.

What symptoms did you have before stem cell therapy?

I couldn’t move my left arm. My vision was pretty bad. My speech is worse than it is now. I could only make sounds. My balance was very, very bad and that’s about it.

What improvements have you noticed since your stem cell treatments?

My speech is better. My eyesight is better. My arm coordination is better. My balance overall and better overall well-being.

How has this treatment changed your life?

It improved my quality of life, so much so that I’ve returned now for a second treatment.

What would you tell others who are considering this treatment?

I would say obviously, do your own research but from my point of view, it’s very safe. The medical science is explained. Everything is there on the web site if you look at it and do your homework. I wouldn’t hesitate coming. If I knew before, I would have came earlier.

Heart failure patient has 3 normal EKGs after stem cell therapy

I was diagnosed 20 years ago. My heart was stopped up. I have 11 stents in my heart. When they put in (stents) nine, ten and eleven they blocked an artery and caused me to have a heart attack. Then 4 years later, I went to the doctor and he did an EKG and he said he needed to do a nuclear scan. That was in May 2011. In July of 2011 he did a nuclear scan and then called me and told me there was nothing else he could do for me.

A friend of mine in Corpus Christi told me about stem cells in Panama. So I checked into it and I came down in October of 2011 and had a treatment.

[Mr. Gray received multiple doses of human umbilical cord-derived mesenchymal stem cells over the course of several days.]

I didn’t feel anything for 30 days. Then I started feeling better and really felt good. I went to the doctor in January of 2012. He did an EKG and walked in and said, “What have you done?” I said, “What are you talking about?” He said, “You have a normal EKG. You’ve never had one of these before.“ So I asked my wife, “Do you think I ought to tell him?” This was in St. Dominic’s Hospital in Jackson Mississippi; the one that had caused me to have the heart attack. So I asked her, “Reckon I ought to tell him I had got stem cells?” She said, “Yes.” So I told him. He looked like I had cut his throat. He was white as a sheet and he wanted to know, “How did they do it?” and I told him.

Since then I have had 3 normal EKGs. The last one was about 2 months ago.
Well, I had another treatment about 11 months later and it fixed my kidneys the second time. The first time it fixed my heart. It didn’t do anything else but then the second time it fixed my kidneys. I had horse shoe kidneys and I was operated on when I was 33 years old, 35 years old and now I’m 69. My kidney had grown together and my kidneys have been bad my whole life but now they’re fine.

Umbilical Cord Stem Cells: Regeneration, Repair, Inflammation and Autoimmunity – Neil Riordan PhD (Part 2 of 2)

In part 2, Dr. Riordan discusses how mesenchymal stem cells can affect tissue repair in spinal cord injury and in heart failure; benefit to heart is not the actual MSCs modeling new tissue. It is due to the trophic effects of MSC secretions; In rats, severed spinal cords re-grew after MSCs were implanted but the human MSCs did not form new cord tissue. The trophic factors secreted by the MSCs enable the spinal cord to repair itself.; Trophic factors from MSCs modulate the immune system by blocking clonal expansion of cytotoxic T-cells; There are 35 ongoing clinical trials using mesenchymal stem cells for autoimmune diseases; Safety of donor MSCs; Every mother has MSCs from each baby she has carried; Mothers have a lower incidence of autoimmune disease; Lifespan of mothers increased linearly with each child up to 14; There are 85 ongoing clinical trials using donor MSCs. Allogeneic MSCs from bone marrow have been approved in Canada and New Zealand to treat graft vs. host disease; limbal cells used in corneal transplants are MSCs; MSCs are useful in preventing donated organ rejection; glioma growth was found to be inhibited by MSCs; MSCs eliminated breast cancer in rats.

VIDEO – The Science of Mesenchymal Stem Cells and Regenerative Medicine – Arnold Caplan PhD (Part 6)

In part 6, Prof. Caplan discusses Trophic properties of mesenchymal stem cells; MSCs for heart disease; MSCs homing to heart injury site and also to skin incision site; MSCs limit left ventricular thinning following infarction; Trophic properties of MSCs: anti-apoptotic, anti-fibrotic, anti-scarring, angiogenic, mitotic; phase 1 data for allogeneic MSCs show fewer arrhythmias, prompt heart rate recovery, and improved lung function; autologous adipose tissue-derived stromal vascular fraction for treatment of chronic heart disease; Active mesenchymal stem cell clinical trials around the world; Induction therapy with autologous MSCs in kidney transplants; MSCs can coax neural stem cells to become oligodendrocytes, curing mice with MS using allogeneic human MSCs.

Stem cell therapy for spinal cord injury: The Spinal Cord Journey

A short film about three spinal cord injury patients who share their stories of tragedy, hope and recovery following stem cell treatments for spinal cord injury at the Stem Cell Institute in Panama City, Panama. See them demonstrate their improvements by lifting themselves up, standing and even walking after stem cell therapy.

Stem cell therapy for spinal cord injury: Daniel Wiest

Stem cell therapy for spinal cord injury: Trish Stressman

Stem cell recipient Trish Stressman discusses her recovery from spinal cord injury after undergoing stem cell therapy at the Stem Cell Institute in Panama City, Panama. Ms. Stressman has regained control of her core and is now able to stand and walk with a walker.

I now have my abs, back, obliques, hip flexors, and glutes all contracting!

“My name is Trish Stressman. On May 26, 2007 I was in an ATV accident and suffered a burst fracture of my T-6 vertebrae, which left me with a bruised spinal cord. I was labeled a complete spinal cord injury with no movement or feeling below my T-6 injury line. Two years later I found out about Cell Medicine. I wish that I would have found out even earlier because it was great to have “hope” again. I went to Costa Rica for my stem cell treatment. The facilities there were great. They were very clean, professional, organized and modern. The Dr.’s at Cell Medicine and at the Cima Hospital were amazing. They always took lots of time with me and they truly cared about me and my recovery. I always felt safe and knew I could contact them at any time. The Physical Therapy there was also amazing. Within two months of getting the umbilical cord blood and my own bone marrow stem cells through intrathecal injections and IV’s I gained a lot. I now have my abs, back, obliques, hip flexors, and glutes all contracting! I am working now to bring them to full strength and they are almost there. I can stand for an hour now locking my own hips in place while not placing my hands on any support. My knees are not locking on their own yet but I hope to gain that back in the future.”

– Trish Stressman

Stem cell therapy for spinal cord injury: Juan Carlos Murillo

Juan Carlos Murillo is a commercial airline pilot who suffered spinal cord injuries in 4 separate areas of his spinal cord. Doctors told him that his injury was “complete” and that he would never walk again. After completing four rounds of stem cells at the Stem Cell Institute in Panama City, Panama, Juan Carlos is walking again, driving a car and has recently passed his commercial airline pilot physical examination. He expects to begin flying again for an airline within the next few months.

“The Stem Cell Institute states that stem cell therapy is not a miracle cure, but I think for us, the patients, our parents and all of our relatives, it is a miracle cure…”

UPDATE May 2011

Juan Carlos Murillo is a commercial airline pilot who suffered spinal cord injuries in 4 separate areas of his spinal cord. Doctors told him that his injury was “complete” and that he would never walk again. After completing four rounds of stem cells at the Stem Cell Institute in Panama City, Panama, Juan Carlos is walking again, driving a car and has recently passed his commercial airline pilot physical examination. He expects to begin flying again for an airline within the next few months.

“The Stem Cell Institute states that stem cell therapy is not a miracle cure, but I think for us, the patients, our parents and all of our relatives, it is a miracle cure…” – Juan Carlos Murillo

Before he received stem cells, from the waist down, Juan Carlos had no sensation, no movement and was suffering from significant neuropathic pain. He was classified a ASIA “A”. After his first course of stem cells in November 2008, his neuropathic pain was reduced on a scale of 1 to 10 from a 10 beforehand to a 3 afterwards.

His second course of stem cells in February 2009, Juan Carlos starting experiencing movement in his left leg and feeling in certain areas of his leg. He also started gaining muscle mass.
At the time of his third round in June 2009, Juan Carlo was driving an automatic car with his left leg and taking his first steps with a walker and crutches. He had about 80% sensitivity in his left leg.

Juan Carlos received his fourth round in November 2010. By that time, he had recovered his right leg and discontinued using crutches to walk. He was now able to walk with a cane and drive his manual transmission car. He now competes in 4×4 races.

He has now passed his commercial pilot physical. He has started flying again and expects to be employed once more as a commercial pilot within the next one or two months.

November 2010
I am a commercial pilot. On May 13th of 2008 was in a plane crash in the town of Cartago in Costa Rica. As a result of this accident I suffered a complete lesion at L1 and fracture of T12, L1 and L2. I had two surgeries in Costa Rica and one in Chile to stabilize my spine leaving me with 8 screws and 4 titanium rods from T11 to L3 and a titanium spacer for my L1 vertebrae. After this my condition did not improve. I had complete paralysis from the hips down, suffered from neuropathic pain, which on scale from 0 to 10, most commonly reached 10. After returning from my last surgery I was offered stem cell treatment with stem cells from umbilical cord which began in October 2008 with five intrathecal (lumbar puncture) injections. A few weeks after finishing this treatment my neuropathic pain become less common and mostly low-intensity. I also regained bladder control. I received a second treatment in February 2009 with 5 other applications. After this I began to notice changes in my legs with some muscle contractions and sensitivity in certain places. I continued my physical therapy and was able to have better contractions and started to regain strength and contractions in new places. I also regained my bowel function and sexual function. My last treatment was in June 2009 with five intrathecal and 2 intravenous injections of stem cells. After this treatment I could stand up and take a few steps on crutches because I had regained enough strength in my left leg and had already started to have movement in my right leg. As of this writing (October, 2010) I am able to walk without any aids or appliances. I have recovered almost 100% of my right leg and over 80% of my left leg. I have resumed my daily activities like driving and walking. I recently I passed my physical exam and now can fly again. In recent tests and pictures taken of my spinal column there is still a lesion at L1 but I continue walking. I am continuing to recover day by day while in the next few days I will go back for another treatment with the hope that I will be able to be as normal as possible.

Stem cell therapy for spinal cord injury: Dimitrija Krcoski

This is a spinal cord injury patient walking. He had a T8 injury and had been in a wheelchair for 10 years. This video was taken one month after receiving Adult Stem Cells. He received stem cells from umbilical cord blood and umbilical cord matrix.