Stem Cells Lessen Suffering for People with Multiple Sclerosis

The redistribution of a patient’s own adult bone marrow cells as a method of stem cell treatment may lessen the suffering of their multiple sclerosis symptoms.

Professor Neil Scolding of the Institute of Neurosciences at Bristol University’s Frenchay Hospital is researching the use of adult bone marrow stem cells as a therapy treatment for MS.

This type of cell is already used to treat other common conditions such as cardiac disease. They can replace damaged cells by reforming and regenerating.

The scope of stem cell treatment is expanding everyday says Scolding. The Multiple Sclerosis Ireland organization will be hosting him this weekend at their annual conference.

“In the last three or four years we’ve found that stem cells have a number of properties that make them particularly valuable for [ treating] multiple sclerosis. We used to think of stem cells as an opportunity to replace another cell, but it turns out that there can actually be many more things: we can stimulate a local cell or suppress inflammation in its immediate surroundings, which is very valuable in MS,” he says.

The procedure would involve removing bone marrow from the patient and injecting back into the bloodstream making it rather straightforward. The cells would travel almost instinctively to those areas of the body that need attention says Scolding.

“When the cells are injected, they know where to go and from there we hope they will help the tissue to repair,” he says.

Well documented work with other stem cell therapies gives his current research a boost says Scolding. Proof backing up the scientific grounding of treatments in regards to stem cells used in procedures is cited in papers documenting years of successful bone marrow transplant recipients.

“One of the advantages of using bone marrow stem cells is that people for very different reasons have had bone marrow transplants, and they also got those cells,” he says.

“And that means we’ve got 30-40 years’ worth of clinical experience to prove that they are safe and don’t form tumors. They come from the patient and go back to the patient.”

However, as they continue to draw more controversy, embryonic stem cells are falling further behind in terms of research. Many people consider embryos an unethical source of stem cells because it involves the destruction of human embryos.

In contrast to their adult stem cell counterparts, embryonic stem cells are not as reliable says Scolding.

“Quite apart from the ethical questions, there are also very serious biological reasons why embryonic stem cells at the moment are not safe enough to use in therapy,” he says.

“They can form tumors and there is a question of rejection because you are introducing the stem cell into a different patient.”

Scolding says that the answer to the fight against a wide range of health issues can be found in adult stem cells. Before embryonic stem cells can be used as a treatment of any sort, they will need to prove themselves. The process could take at least 10-15 years, if ever added Scolding.

“People are thinking very seriously about using stem cells to treat Parkinson’s disease and diabetes,” he says.

“With MS, we’re not at the stage where we have a lot of results yet, but it’s the beginning of what we hope will be a long journey.”

19 Year Old Suffering from Cerebral Palsy Makes Dramatic Improvement

A breakthrough in the treatment of Cerebral Palsy was announced today. The safe and non-invasive procedure was performed on 19-year-old Gabor from Hungary using neural stem cells. The treatment was administered at Tiantan Puhua Neurosurgical Hospital which is famous for its world leading treatments for stroke and Parkinson

Media Supresses Adult Stem Cell Breakthrough for Heart Valves

Heart disease is a silent killer, but equally hushed are reporters, politicians and activists who disregard a politically incorrect cure. Grown from your own body

Heart Organ Performance Dramatically Improves with Adult Stem Cells

Some of the first evidence that stem cells could be used to treat patients for heart failure has now come to fruition. The much-hyped theory now seems more like reality with the investigations resulting in significant clinical benefits.

To treat patients, instead of using more controversial embryonic stem cells, scientists used adult stem cells. The two studies showed marked improvement in the patients

Girl with Rare Genetic Condition Travels for Stem Cell Treatment

More than 60 million stem cells will soon be injected into a little girl afflicted with an uncommon genetic condition. In less than a week, she will fly to China accompanied by her mother, aunt, and cousin.

Suffering from Glucose Transporter Deficiency, the nine-year-old Brooke is unable to function like a typical child and suffers from cerebral palsy like symptoms. She cannot stand for longer than seven minutes without holding on to something, and her brain abnormalities limit her speech as well. The condition is caused by a genetic mutation of the gene that processes glucose from food and transforms it into fuel for her body.

The illness is better known as GLUT-1, and Brooke is the 83rd person in the world to be diagnosed. She will however, be the first person in to ever be treated with stem cells in an effort to reverse her condition.

The stem cell injections are not available in the United States and they may never be. The procedure is completely safe according to the Chinese research center and hospital.

Brooke’s parents, Ed and Vicki, say that they would travel to the end of the Earth to help their child. For them, any risk, if it even exists, is negligible.

“Brooke is very blessed to have them as parents,” aunt Cindy said. “I believe God knew what he was doing when he hooked them up.

“Things happen for a reason, and Brooke came to them because she needs extra care. She landed in the lap of parents who will go halfway around the world for her.”

Brooke could perhaps manage the severity of the symptoms with a low-carbohydrate, high-fat diet according to her neurologist at the Children’s Hospital of Wisconsin. Her doctor is not entirely sure if Brooke even needs the procedure, considering GLUT-1 is a nonfatal disease says Vicki.

“In my eyes, if it can help her, we’re going to do all we can,” Vicki said. “That’s what it pretty much boils down to.”

The research done in China in regards to umbilical cord blood stem cells has reassured Brooke’s family. Only three patients out of 100 that were treated for cerebral palsy at the clinic in China did not see positive results. That translates to a 97% rate of effectiveness for the particular treatment. Kirshner, who is a registered nurse working as a link between China and American patients said that no patients have experienced any kind of negative consequence due to the stem cell injections.

“There is no risk to the child. The treatment itself is extremely safe,” Kirshner said. “Umbilical cord stem cells have been used in this manner well over 20 years.

“I would never ask any mother to put their child through this process if I thought there was a possibility that it would harm this child in any way.”

GLUT-1 was first diagnosed in 1991 by Dr. Darryl. Since the injections are not approved for use in the United States at this time, he did not want to say if he was for or against the treatment.

“It’s not something that he could say, ‘This is something you might want to do,'” Vicki said. “He also didn’t say, ‘I think you’re crazy; this is a pipe dream; don’t do it.’ It wasn’t one way or another.”

The family doesn’t need any additional persuasion. They trust the stem cells will help, and the plane tickets that have already been purchased are an indication of their belief. Within three to six months following the treatment, they hope Brooke exhibits signs of progress with her motor skills. But the also remain guarded and know it won’t be a miracle cure for GLUT-1.

“I’m going to be watching Brooke and every move she makes like she’s under a microscope,” Vicki said. “We’re hoping to see some improvements and cognitive change.”

As for others who have children suffering from brain abnormalities, the family hopes that Brooke’s improvements will not go unnoticed for them.

“Just getting the word out that this might be a possibility, to share with other families a success story would be incredible to me,” Vicki said. “It could be a success story for them, and they could see their child develop in ways that they might not see otherwise.”

Cord Blood Stem Cell Treatment for Woman with Spinal Aneurysm

Dawn has wanted to visit the second floor of her new home ever since she moved in. But it is something that she has to this day, been unable to do.

However, physically going to the second floor is now a few small steps closer to becoming a reality.

Seeking treatment for a spinal aneurysm she suffered when she was 20 years old, the now 28-year-old Dawn traveled to the costal city Shenzhen near Hong Kong. Her mother Phyllis accompanied her on the trip.

She used a wheelchair to get around but was able to recover some movement and ability in her limbs over the years. Then last year, she found another treatment that could help her make much greater progress: stem cell injections.

Instead of using controversial embryonic stem cells, the Chinese clinic uses cells harvested from umbilical cord blood. Autism, heart failure, Alzheimer

Man’s Own Fat Stem Cells Transplanted into Heart

In an experimental treatment for angina and heart disease, doctors have implanted adult stem cells derived from a man’s fat tissue through liposuction into his heart.

Although he is doing well, it could take up to six months to see whether the cells repaired the damaged vessels in the 67-year-old man according to the Gregorio Maranon Hospital in Madrid.

He is the first patient to receive the treatment.

“Cardiologists … have implanted adult stem cells from fat in the heart of a patient for the first time in the world,” the state hospital said in a statement.

Scientists trust that therapy for a variety of conditions is feasible in the future since stem cells are master cells that can change in any variety of cell or tissue.

In conjunction with doctors at the Texas Heart Institute in Houston, the new treatment is being developed with cardiologists at the Spanish hospital. The study will involve 36 individuals and the first patient was treated on January 30. His name has not been made public.

Emerson, an American colleague of Spanish cardiologist Francisco extracted the stem cells together.

“In just five hours approximately the cells were extracted, purified, selected and implanted with the aim of regenerating new blood vessels which may allow them to flow blood properly to the heart of the patient”, the hospital said.

In only two hours, 28 million cells were set for implanting. The reason for this was that unlike other varieties of stem cells, those extracted from fat do not need to be cultured for three weeks.

The cells were implanted with the use of a catheter by plastic surgeons, the same doctors who were also responsible for originally extracting the fat tissue from the patient

Stem Cell Therapy for Boy After Near Drowning Leaves Him in Vegetative State

Slumped in a blue reclining chair, Michael sits in his father’s front room.

Underneath the teenager’s sweatpants, the fifteen year old wears powder-blue diapers.

Moving forward and to the right, his head droops, only to jerk up as Michael tries to make eye contact with others.

After traveling 9,000 miles for adult stem cell therapy, this jerky head movement could perhaps be a sign that the treatment he received is working.

Doctor’s injected stem cells several times into his bloodstream and spine while his father sat hoping for positive results in the Chinese hospital.

And even though David, Michael’s father, is afraid to hope that his son will make some sort of recovery because he doesn’t want to be heartbroken again; he is equally afraid not to.

“Believe me, when you’re in this condition, you look for any change you can,” he said.

After becoming intoxicated at a beach party with other teens, the then fourteen year old Michael drowned. He was resuscitated but the damage was done. Extensive brain damage occurred when he went without oxygen for a period between 10 and 30 minutes.

Just like Terry Schiavo was lost in a vegetative state, Michael has been locked in this persistent condition since his drowning in June of 2005.

After communicating with other parents of brain-injured children on an internet support group, David decided to look into stem cell therapy.

“Parents have to be careful. It’s your child. You’ll do anything. People will take advantage of you,” said David, who added that there are a number of alternative therapies available.

But he said that the most hope was offered by adult stem cell therapy.

“It’s not a magic bullet. On the other hand, it’s not black magic, either,” he said.

Certain stem cells therapies are being used in the United States today, however, the procedure is limited to experiments and specific diseases such as leukemia.

Since a patient receives healthy bone marrow stem cells from a donor to replace abnormal ones, a bone marrow transplant is technically stem cell therapy.

But there are no stem cell therapies available for neurological injuries such as Michael’s.

David’s internet research returned few results. He found that only three countries, the Dominican Republic, Mexico, and China, offered the kind of stem cell therapy Michael needed.

It was a mix of eastern and western medicine, and the $20,000 six-week hospital stay included fee, that made China his choice.

David and his wife of two years, Dana, flew to China with Michael in late November. It was trip made possible with money withdrawn from David’s 401(k).

Michael was in and out of wheelchairs and airline seats during the 30-hour trip. Not a simple task considering Michael is basically as David says, a “152 pound infant”.

Michael’s spinal cord was injected with four doses of umbilical cord stem cells over the six-week course of treatment. A fifth cord blood stem cell infusion was administered intravenously.

The immature stem cells should stimulate a response within the next three months according to the Chinese doctors.

“What I’m personally hoping for is in the next couple of months (that he’ll be able) to give me a yes or no,” David said. “(The) long-term goal is that he’ll come back, ‘Where have I been for a year-and-a-half?’ ” his father added wistfully.

The things that Michael can do are still more difficult to list than that things he cannot. He can’t swallow anything, not even his own saliva, so he has a feeding tube to help him through the process. None of his extremities move voluntarily, but he still has sensation in all of them.

Michael has no response when his father plays music that Michael downloaded before the accident. His eyes cannot track colors or movement.

He laughs randomly, and occasionally – heartbreakingly – cries.

Michael was plagued by a skin condition since the brain injury, but that has at least disappeared.

But it is difficult to measure more signs of progress.

David has not slept through one single night since the accident because Michael hasn’t either.

A baby monitor in his room alerts his father when Michael wakes up. He may just be awake; or it’s possible that his position needs to be shifted or that his diaper needs to be changed. Michael can’t tell his father.

David wakes up every time Michael does. His father says that Michael’s body clock appears to have been permanently injured from the brain damage.

“It would be pretty bad if he died on my watch,” said David. “Right now, it’s just maintaining him physically until the cognitive part kicks in.”

For now, David just focuses on the moment that is right in front of him – on surviving that one, and the one immediately following.

Until Michael reaches the age of 22, he will attend Silver Sands School during the day.

David and his son had talked about Terri Schiavo and how her life ended. David thinks back to those past moments on occasion.

“If you’re asking me what he would have wanted, he would not have wanted this,” David said. “But he does not have that choice.”

For now, David is looking for proof that he has gotten even the smallest fraction of his son back, evidence that the adult stem cell therapy is working.

“All we gotta do is make it through another day, another day, another day. I can’t look way into the future,” he said.

“If I look too far, I might see the truth, you know, and I don’t know if I want to.”Stem Cell Therapy for Boy After Near Drowning Leaves Him in Vegetative State

Naples Man Fights Against Heart Failure with Aid of Stem Cells

Another seven or eight months, and Mel would be dead. He was running out of time since he found no sympathy from congestive heart failure.

But then adult stem cells came into the picture, quite literally, as a potential life saving treatment. Mel’s son watched a program on The Discovery Channel about adult stem cells. They were injected to improve heart function and grow new muscle after being harvested from a person’s own blood.

The Bangkok Heart Hospital became the 72-year-old Mel’s destination of choice, since adult stem cell therapy is only in its infancy in the United States in terms of treatment and research.

Thailand became the country where Mel would receive his treatment.

“I feel 100 percent better,” Mel, a retired businessman in Naples, said. “I can walk around and do a lot of things without getting out of breath. Of course, there are a lot of skeptics in the medical field.”

Dr. Zannos, has become an advocate of the procedure; and for those who are skeptical that the procedure really had any effect, the Florida cardiologist is sponsoring a free seminar on adult stem cell therapy for heart failure.

Scientists Investigate Adult Stem Cells Potential to Heal Diseased Heart

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