Paralyzed Man Will Get Indian Stem Cell Treatment

Helping his significant other with the daily chores would be a dream come true for Andrew. This may seem odd, but running out for groceries, mowing the lawn, even a day spent cleaning the gutters would be ideal.

It was these activities, or work as most would put it, that Andrew took for granted a year and a half ago. Not surprisingly, most of us probably feel the same way. But then a motorcycle crash left the 41-year-old paralyzed, and unable to experience even the mundane things in life.

But a private Indian hospital has accepted him as a patient, and on June 20th he will receive stem cell treatment that will potentially restore his ability to walk.

When a driver changed lanes without checking, he swerved his motorcycle to avoid an accident, but lost control of his bike changing his life forever on October 1, 2005.

“I’ve gone down a big ditch on the shoulder of the round-about and I don’t remember this, but I ran through a tree and came back onto the road. All I remember is coming to and trying to get up and then it was like, ‘hang on, I can’t move my legs’.”

He was told that he would be paralyzed from the chest down after being flown to the Princess Alexandra Hospital in Brisbane. He had damaged his spinal cord between the T6 and T7 vertebrae.

At the hospital Andrew met an important woman. Following stem cell therapy, Sonya regained sensation in her legs and her control over her bowel and bladder as well. After being treated by Dr. Geeta Shroff at the Delhi Nu-Tech Medicare facility, she made international headlines due to her amazing progress.

Sonya’s life was similar to Andrew’s once. She was told that she would need to figure out a way to live with her disability, and Andrew knew her when she was in the same state. After stem cell therapy, when she was once again wiggling her toes, Andrew watched a news story about her on television. By this time, Andrew had already talked to her about her stem cell treatment after tracking her down while she was still in India.

“She told me about Dr. Shroff and her treatment and obviously she was over the moon,” he said.

“She had gone from being in a wheelchair for the rest of her life, to standing again. In two years she has been told she will be walking, unassisted. It may not be a normal gait, but who cares? It’s something.”

Andrew ended up booking his own procedure after doing extensive research on stem cell therapy and contacting Dr. Shroff himself.

He will start his first series of stem cell injections a day after he arrives in India with the rest of his young family. His household partner, Sarah-Jayne Matthews will fly with him as well on June 19th.

He will need to stay in India for 2-3 months to complete the entire course of treatment. They are admittedly a bit short on cash for the entire endeavor despite numerous fundraising efforts and the help of friends and family.

They want to be able to afford a camcorder to track Andrew’s progress. So they can keep in touch with friends and family, a 3G phone would also be nice. And the children need to continue their school work while overseas so purchasing a notebook computer is also in order.

Within the medical community, Dr. Shroff refuses to publish her results and this has drawn criticism from medical professionals. Andrew understands he is taking a risk, but he has seen all the proof he needs.

Andrew has seen and talked to patients who have gotten better, dramatically in some cases. So the fact that Shroff has been labeled as a quack by experts is irrelevant to Andrew, and misleading.

Any chance he has to regain the part of his life he lost is worth taking according to Andrew. He spent his life before the accident being active and will travel to India to potentially restore his body.

“I’ve never ever given up hope that I will walk again and I never will,” he said.

“From day one, I have researched all the different stem cell procedures around the world and this is my best chance. This is the best chance that is available to me.”

“There is a fear factor in everything you do. That’s normal. There could be repercussions from it, but I’m willing to accept that.”

“I don’t expect to go in there and suddenly be able to walk out. That’s aiming too high. But it’s a ‘what if’ situation. What if I didn’t go and what if I was one of the ones who did get out of their wheelchair?”

“For that, I’m willing to take the risk. Because I have nothing to lose and any improvement is 200% on what I have now.”

Umbilical Cord Blood Stem Cells and Their Importance

The placenta and umbilical cord contain blood that is jointly referred to as umbilical cord blood. Following the delivery of a baby, the blood is extracted right away. This blood is an extremely rich source of adult stem cells. Stem cells can begin replenishing or repairing old cells in the body by adjusting at anytime. And by having the capability to transform into new brain, blood, heart, and other types of cells; stem cells can bee viewed as the architects of the human body.

Information about birth defect, various diseases, and other ailments, can be discovered by scientists through stem cell research. The underlying secrets responsible for deformities and genetic diseases can be discovered with study. Stem cells have the power to create any cell the body needs by multiplying many times over until the body has repaired itself.

There are a vast number of conditions and diseases that are currently being treated using umbilical cord blood stem cells.

Extensive research is being conducted the benefits of cord blood stem cells in ailments like Brain tumor, Ovarian cancer, Small cell lung cancer, testicular cancer, Rheumatoid Arthritis, spinal injury, diabetes, Parkinson

Public Confused About Adult and Embryonic Stem Cells

In a letter published on May 22nd, a man named Greg equated embryonic stem cell research and adult stem cell research. The difference could not be more apparent and thus a correction is in order.

Few news stories today present the two types accordingly and instead fail to distinguish the significant differences between the two. It is crucial to understand the difference and the media has perhaps contributed to the confusion today.

The most important distinction to make is that unlike embryonic stem cell treatment, adult stem cell treatment is effective. As a result of adult stem cell research, more than 70 existing medical treatments have been developed. Even one simple treatment has yet to be yielded as a result of embryonic stem cell research.

Contrary to the comments made in Greg’s letter, the statement “great future potential” can be tied exclusively to adult stem cell research, not embryonic.

The second important point to make note of is the ethical nature of adult stem cells. Without causing harm to anyone, the placenta at birth, umbilical cord blood, and other types of non-embryonic tissue, are all sources of adult stem cells. However, without destroying human embryos, embryonic stem cells cannot be obtained.

Muscle Building Stem Cells for Regenerative Therapy

Responsible for producing the almost bursting biceps of body builders and the wash board abs of fitness fanatics, a new report confirms the existence of some uncommitted stem cells residing amongst those of the muscle. For people that suffer from muscular dystrophies and an assortment of other muscle-wasting diseases, the discovery could show the way to new muscle-regenerating therapies. These would include stem cell-replenishing drugs and cell transplantation regimens. According to researchers, these treatments could also serve a dual purpose by also keeping people strong as they age.

A mix of cells already dedicated to their muscular destiny and other cells that behave more like versatile stem cells make up part of the so called satellite stem cells. The breakthrough was made by an Ottawa Health Research Institute team led by Michael Rudnicki. The cells had commonly been considered by scientists as a homogeneous population of devoted muscle progenitors. In the lab, the regenerative reservoir of cells that mice have was successfully replenished when Rudnicki’s team injected the “satellite stem cells” into the muscles of the mice.

“We’ve found that there are two types of satellite cell–90% that are already committed to becoming muscle and another 10% with characteristics normally attributed to stem cells,” Rudnicki said. “It’s not been shown yet, but these muscle stem cells might even have the capacity to make other tissues, such as bone and fat.”

“We’ve also shown that these satellite stem cells, when transplanted into muscle, can repopulate the regenerative cell niche. This is a very significant advance in our understanding of satellite cell biology that will require us to rethink decades of research. It also opens new avenues for therapeutic treatment of muscular diseases.”

Each of which includes hundreds of nuclei, skeletal muscle fibers are essentially long tubular cells. Satellite cells are found in between the coating of glycoproteins and collagen that surrounds the muscle fiber. Responsible for the repair, growth, and maintenance of skeletal muscle after birth, the existence of satellite cells were first revealed in the 1960’s. When the stress of trauma or weight-bearing presents itself, the cells which are by and large quiet, jump into action.

Still, Rudnicki said that uncertainty still exists in regards to the mechanisms that control the development and identity of the satellite cells. Muscle cells that had changed back into a more primitive state by reverting or dedifferentiating was once thought to be the path that satellite cells followed from their original muscle cell state. This was suggested by earlier studies.

Isolated from mouse muscle, the molecular profiles of the satellite cells was closely observed by researchers in the new study.

Defined by the inactivity or activity of a gene called Myf-5, the satellite cells consist of two classes.

A significant difference in the satellite cells’ behavior was made clear by the genetic difference. A characteristic commonly seen among stem cells, asymmetric division, was observed in the satellite cells without active Myf-5. Exhibiting another Myf-5 positive cell and stem cell-like capacity for self renewal, the lopsided cell division produced one “daughter” like its parent.

The satellite cells continued on the path to becoming muscle tissue when they were injected into the muscles of mice with the Myf-5 switched on.

In contrast, transplantation of Myf-5 negative cells “extensively contributed to the satellite cell reservoir throughout the injected muscle.”

Diseased muscle can be directly transplanted with satellite stem cells. Researchers made this conclusion while noting that the identification of markers enabling their prospective isolation from human muscle tissue could be found in the molecular characterization of satellite stem cells.

“Alternatively,” they added, “understanding the molecular regulation of satellite stem cell symmetric versus asymmetric cell division will lead to identification of biologics or small drugs that specifically target the relevant pathway leading to satellite stem cell expansion.”

False Hope Comes with Embryonic Stem Cells

Lobbying for the passage of a bill authorizing federal funding for embryonic stem-cell research, Rekha and others who have been affected by Lou Gehrig’s Disease (ALS), were in Washington D.C. earlier this month. On May 18th, Rekha wrote a column titled, “ALS Activists Fight for Research, Cling To Hope”. The material was infuriating and heartbreaking at the same time; Rekha believes that embryonic stem cells “may hold the key to finding a cure.” However, she was mistaken.

For the treatment of injuries and diseases, only adult stem cell have been proven effective.

Even the American College of Pediatricians (ACP) called for an end to embryonic stem-cell research, “which prolongs needless suffering by delaying the development of more promising adult stem-cell treatments and cures.” On May 14th, this entire medical organization backed up the fact that embryonic stem cells are just not necessary.

Exclusive use of adult stem cells has resulted in the successful treatment of dozens of conditions and diseases over the last decade. The ACP cites these strong pro-adult stem cell results further noting, “catastrophic results…producing the wrong tissue, forming tumors and triggering immune rejection,” when describing the abysmal failure that embryonic stem cell trials have produced. Asserting that it, “steals resources away from the established utility and potential of adult stem-cell research”; the medical group denounced embryonic stem cell research as a tremendous waste of money and resources.

Afflicted patients and their families continue their journey on a path that leads to nowhere because of people like U.S. Senator Tom Harkin who is a sponsor of the embryonic stem cell bill.

Heartless and cruel are only a few of the words being used to describe opponents of embryonic stem-cell research. But offering false promises to millions of desperate people who are suffering from diseases and conditions that could be treated with adult stem cells right now may be even more heartless.

U.S. Citizens Denied at Home Leave Country for Stem Cell Treatment

Two years ago, Tori suffered brain injury when she was caught up in a car accident. She was left powerless to talk or walk, and her family decided to do anything they could to help her be who she once was. The opted for a trip to China for adult stem cell therapy. It is now three months after her treatment, and 16-year-old Tori can take a cookie out of her father’s hand. A task that would have only been a dream prior to the stem cell treatment.

Tori’s family is not alone with their frustration and impatience towards U.S. scientists. The number of American’s the feel the U.S. is too sluggish in determining whether stem cells are safe and effective is growing, and to get treatment, more are leaving the country as an alternative. Tori’s family chose China because of the limited options in the United States.

Tori’s treatment consisted of acupuncture, aggressive physical therapy, and 50 million adult stem cells which were spread over a course of five injection. The family paid $20,000 in advance for the therapy.

Tori’s father Tim says that it could take up to eight months to see progress. Her last injection was on February 12th. But already her chewing, eating, and swallowing have substantially improved.

The family hopes for even more improvement in Tori, who can now vocalize more and can finish of an entire apple.

Tori was trapped underwater for about 20 minutes when a car she was a passenger in rolled over and ended up in a canal. It was June 2005, and 14 year old Tori had dreams of becoming a Stanford educated doctor. She enjoyed snowboarding and dancing.

Tori’s story has helped other families to make the decision to travel overseas. The website PrayForTori.com prompted at least eight other families to make the decision. On Utah girl who suffered brain injury due to a car accident is currently at the same hospital in China with her family at this very moment.

Tori’s family plans to do another round of stem cells therapy next year.

“It is the thing that will help (Tori) the most eventually, I’m convinced of that,” said Tim, who urges increased funding for research.

“In the end, it’s just going to help so many people. I don’t see how we can not do it.”

Adult Stem Cells Engineered to Produce Insulin

Friday, U.S. and British researchers reported that diabetes could be treated by using stem cells taken from the umbilical cords of newborns. The cells could be engineered to produce insulin.

Insulin-producing cells in the pancreas are damaged by diabetes. Researchers were able to take stem cells, expand them into a large number, and direct them to be similar to the insulin producing cells. The cells could potentially be used to fill the void left in the pancreas due to the damage that is caused by diabetes.

3-Year-Old Fights Leukemia with Umbilical Cord Stem Cells

A stem cell transplant was the final option that a three-year old girl had to save her life. She is now secluded in an isolation unit of the same hospital she received stem cell treatment in.

A worldwide donor search was initiated when Eva was diagnosed with leukemia 5 months ago.

A compatible match was found in the United States, and bone marrow was created using the stem cells from the donor baby

Perianal Fistulas Curable with Adult Stem Cell Treatment

Spanish researchers say that a cure for perianal fistula can be found in a patient’s fat. The stem cells in the fat to be more precise.

According to Damian Garc

Parkinson’s Disease Seemingly Cured with Indian Stem Cell Therapy

America citizen Andrew traveled to Manipal hospital in Bangalore for stem cell treatment and recovered from Parkinson’s disease after U.S. doctors were of no help.

The trip to India was a last resort for Andrew, who had been suffering with Parkinson’s for more than 15 years. Treatment at U.S. hospitals had provided zero results so he decided to try stem cells as a last go. His personal comfort and feeling of well-being have increased, but more noticeable to others is the fact that his tremors have reduced significantly and he can now walk without support one year following the treatment. The last few months have brought the elimination of his Parkinson’s medication as well. For those suffering with Parkinson’s disease, Andrew’s recovery will give them plenty of hope.

Said R Basil, M.D. and CEO, Manipal Health System, “The successful clinical outcomes from our stem cell research program have given us the confidence to share this new hope with the public at large so that a greater number of people can participate in the clinical research for getting relief from major diseases and disabilities.”

To determine the full ability of stem cells in treating disabilities and diseases that no current treatments offer much hope for is the goal for the team of accomplished stem cell research clinicians, led by Chief Scientific Officer of Stempeutics Research Pvt Ltd, Dr. Satish Totey. Using human adult stem cells, the development of stem cell based therapies is the goal of the Stem Cell Research Center.

While delivering his presentation about the remarkable recovery of Andrew, Dr. Venkataramana said, “Stem cell research seems to be promising in regenerating hope to cure PD. This will motivate innumerable patients across the world to explore this new modality. However, we need to observe the long-term clinical effects in large number of patients to decide its role in the treatment of the degenerative diseases.”

According to Dr. Nagendra Swamy, Group Director- Medical Services, Manipal Health Systems, “Stem cell research has attracted wide attention from all medical fields in the world. The research involving human pluripotent stem cells promises new treatment and possible hope for many devastating diseases. This research Centre will promote cutting edge research which can be translated into clinical applications. This would support the in treating the diseases affecting heart, brain, liver, kidney, bone, spinal cord and vascular. This promises to be the future of medicine in coming years and Manipal is proud to be a leader in this science.”

People over the age of 50 make up the majority of those suffering from Parkinson’s. Current treatments cannot halt the progression of the disease, but can only alleviate a few of the symptoms.